Cortical Astroglial Atrophy in Ageing and Alzheimer's Disease

p. 21 1. Function and Dysfunction of the Entorhinal cortex p. 23 1.1 Anatomy and Organisation of the EC p. 23 1.1.1 Subdivisions of the EC p. 23 1.1.2 Lamination and Cytoarchitecture p. 25 1.1.3 Differences and Similarities in Lamination between the LEC and MEC p. 27 1.1.4 Entorhinal-Hippocampal Connections p. 28 1.1.5 Entorhinal-Cortical and Entorhinal-Subcortical Connections p. 30 1.1.5.1 Entorhinal-Cortical Connectivity p. 30 1.1.5.2 EC Connections with Subcortical Structures p. 32 1.1.6 Intraentorhinal Connections p. 33 1.2 Functional Roles of the EC p. 35 1.2.1 EC as Information Transfer and Integration Hub p. 35 1.2.2 Entorhinal Activation and Neuronal Activity in Cognition p. 39 1.2.2.1 Working memory p. 40 1.2.2.2 Long-term Memory p. 40 1.2.2.3 Spatial Representation and Memory p. 42 1.3 Entorhinal Dysfunction in Neuropathology p. 44 1.3.1 EC in temporal lobe epilepsy and schizophrnia p. 44 1.3.2 EC in non-AD dementia and Ageing p. 45